Postoperative Radiation Therapy Improves Survival in Incompletely Resected NSCLC

 

Postoperative Radiation Therapy Improves Survival in Incompletely Resected NSCLC

Journal of Clinical Oncology

 Non small cell lung cancer is the most common lung cancer and the most common cancer killer. The first option one always hopes for is that it is stage 1 or 2 and perhaps a truly limited stage 3 and thus holds the chance at complete surgical removal. This is not the most common scenario but it happens frequently enough but relapses after surgery are not uncommon. Now we do have two monoclonal antibodies and two oral pills to fight this cancer which have amazing results when the tumor has relapsed after  first line therapy.  However it has been unclear what benefit post operative radiation therapy has in limited stages which have been resected with curative intent  This registry-based, retrospective study of patients with incompletely resected stage 2 or 3 non–small cell lung cancer assessed the use and relative outcomes of postoperative radiotherapy, which 1207 (35.6%) of 3395 patients received. Patients who received postoperative radiotherapy had an increased 5-year survival rate compared with those who did not (32.4% vs 23.7%); median survival was 33.5 months and 23.7 months, respectively. That is a big difference


PURPOSE

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