Very Overweight Teens May Double Their Risk of Bowel Cancer in Middle Age

Very Overweight Teens May Double Their Risk of Bowel Cancer in Middle Age

 

WE KNOW THAST OUR DIETS SHOULD HAVE LESS MEAT, LESS HIGHLY SATURATED FATS, LESS RED MEAT, LESS PROCESSED FOODS AND MORE VEGETABLES, FRUITS, NUTS, WHOLE GRAINS AND STAY OFF THE SUGAR OR COMPOUNDS THAT WILL BECOME SUGAR – HIGH FRUCTOSE CORN SYRUP FOR E.G.. WE KNOW THAT THE WRONG DIET INCREASES YOUR LIFETIME RISK OF COLON CANCER AND CANCER IN GENERAL, THIS STUDY, HOWEVER, DIGS DOWN DEEP INTO THE ADOLESCENT POPULATION AND FINDS FRIGHTENING RESULTS mom and dad take heed

Key Points:

  • Adult obesity and inflammation are associated with an increased risk of bowel cancer.
  • Men with a BMI of 27.5 to 30 between the ages of 16 and 20 were twice as likely to develop bowel cancer.
  • Those with a high erythrocyte sedimentation rate of more than 15 mm/h had a 63% higher risk of developing bowel cancer than those with a low erythrocyte sedimentation rate.

Being very overweight in your teens may double the risk of developing bowel cancer by the time you are middle-aged, suggested research published by Kantor et al in the journal Gut. A high level of an indicator of systemic inflammation—erythrocyte sedimentation rate—at this age is also linked to heightened risk of the disease in later life, the study showed.

Adult obesity and inflammation have been associated with an increased risk of bowel cancer, which is the third most common form of cancer among men worldwide. However, less is known about how obesity and systemic inflammation might be influential during late adolescence.

Study Background

The researchers therefore tracked the health of almost 240,000 Swedish men, who had been conscripted into the military between the ages of 16 and 20 in 1969 to 76.

At enlistment, the men had a health check, which included weight, height, and erythrocyte sedimentation rate levels. The men were then monitored for bowel cancer up to 2010, using national cancer registry data.

At the time of conscription, nearly 12% of the men were underweight, while almost 81% were of normal weight. About 5% were moderately overweight; 1.5% were very overweight; and 1% were obese.

Study Findings

During the monitoring period—an average of 35 years—885 of the men developed bowel cancer, 384 of which were rectal cancers.

Compared with those whose weight was within the normal range when they enlisted (body mass index [BMI] 18.5–25 kg/m2), those who were very overweight, with a BMI ranging from 27.5 to 30, were twice as likely to develop bowel cancer.

Among men without known inflammatory bowel disease at the time of their conscription health check, those with a high erythrocyte sedimentation rate of more than 15 mm/h, had a 63% higher risk of developing bowel cancer than those with a low erythrocyte sedimentation rate of less than 10 mm/h.

This is an observational study, so no definitive conclusions can be drawn about cause and effect, but the researchers say that the findings suggest that both BMI and inflammation during adolescence may have a role in the development of bowel cancer. Both factors were independent of each other, indicating that teen BMI may influence bowel cancer risk through mechanisms other than inflammation.

Further studies are needed to better understand the role of life course inflammation and BMI in the development of bowel cancer, concluded the researchers, who added that this may help inform preventive strategies.

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